Premarin Drágeas

Formulações Hormonais comumente prescritas na Menopausa:

Adesivos (Patch)

Preparation Doses Comments
Systemic estrogen therapiesa
Oral estrogen tablets
Micronized E2 0.5, 1.0, 2.0 mg/d
Estradiol valerateb 1.5 mg/d
CEE 0.3, 0.45, 0.625 mg/d Higher doses available
Preparation used in WHI
Transdermal estrogens
Estradiol patch 0.025 to 0.1 mg once or twice weekly
depending on preparation
Corresponds to 0.5 to 2.0 mg estradiol tablets
Diffusion can be different from one patch to another
0.014 mg/wk Preserved bone in women 60 y old
Estradiol percutaneous gel 0.25–1.5 mg qd Corresponds to 0.5 to 2.0 mg estradiol tablets
Can be transferred to persons and pets by skin
contact
Estradiol transdermal spray 1.5 mg qd Estradiol via spray
Can be transferred to persons and pets by skin
contact
Vaginal ring
Estradiol acetate 0.05–0.10 mg/d Systemic levels of estradiol provide relief of VMS;
90-d duration/ring



Estradot (17 ß-estradiol doses de 50 mcg e 100 mcg)